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簡(jiǎn)要描述:表皮生長(zhǎng)因子樣蛋白2抗體免 疫 原;KLH conjugated synthetic peptide derived from human CELSR2: 201-300/2923
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表皮生長(zhǎng)因子樣蛋白2抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
表皮生長(zhǎng)因子樣蛋白2抗體 | CELSR2 | GOY-01K2028 |
商品屬性:
英文名稱: CELSR2
中文名:表皮生長(zhǎng)因子樣蛋白2抗體
別 名;Cadherin EGF LAG
seven pass G type receptor 2 flamingo Drosophila homolog; Cadherin EGF LAG
seven-pass G-type receptor 2; Cadherin family member 10; CDHF10; CELR2_HUMAN;
Celsr2; EGF like domain multiple 2; EGF-like protein 2; EGFL2; epidermal growth
factor like 2; Epidermal growth factor-like protein 2; Flamingo homolog 3;
Flamingo1; KIAA0279; MEGF3; Multiple EGF-like domains protein 3; Multiple
epidermal growth factor-like domains protein 3.
研究領(lǐng)域;神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 通道蛋白 細(xì)胞膜受體 G蛋白偶聯(lián)受體 細(xì)胞骨架 細(xì)胞外基質(zhì) G蛋白信號(hào)
抗體來(lái)源;Rabbit
克隆類(lèi)型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;314kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human CELSR2: 201-300/2923
<Extracellular>
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Drosophila Flamingo is a seven pass transmembrane
cadherin that is necessary for dendritic patterning and axon guidance.
Flamingo mammalian homo-logs play similar roles in neuronal development,
during which they play an important role in cell-cell signaling. Cadherin EGF
LAG seven pass G-type receptors (CELSRs) are multi-pass membrane proteins
that belong to the G protein-coupled receptor family of proteins. Silencing
CELSR2 gene ex-pression results in signficant simplification of dendritic
arbors of cortical pyramidal neurons and Purkinje neurons, which may be due
to branch retraction. In mouse, CELSR1, CELSR2 and CELSR3 are expressed in
the nervous system at early developmental stages, and show expression
patterns in the developing CNS. CELSR2 is distributed at intercellular
boundaries in the whisker and on processes of neuronal cells such as
hippocampal pyramidal cells, Purkinje cells and olfactory neurons. Receptor that may have an important role in
cell/cell signaling during nervous system formation. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類(lèi)型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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