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簡(jiǎn)要描述：慢性粒細(xì)胞白血病33抗體免 疫 原；KLH conjugated synthetic peptide derived from human FARSLA/CML33: 51-150/508
產(chǎn)品型號(hào)：GOY-01K1178廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：174產(chǎn)品分類
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慢性粒細(xì)胞白血病33抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
慢性粒細(xì)胞白血病33抗體 | FARSLA/CML33 | GOY-01K1178 |
商品屬性：
英文名稱: FARSLA/CML33
中文名:慢性粒細(xì)胞白血病33抗體
別 名；CML 33; CML33;
FARS; FARSA; FARSL; FRSA; PheHA; Phenylalanine tRNA ligase 1 alpha cytoplasmic;
Phenylalanine tRNA ligase alpha chain; Phenylalanine tRNA synthetase alpha
subunit; Phenylalanine tRNA synthetase like alpha subunit; Phenylalanyl tRNA
synthetase alpha chain; Phenylalanyl tRNA synthetase alpha subunit;
Phenylalanyl tRNA synthetase like alpha subunit; PheRS.
研究領(lǐng)域；腫瘤 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；57kDa
細(xì)胞定位；細(xì)胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human FARSLA/CML33: 51-150/508
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Aminoacyl-tRNA synthetases consist of a family of
enzymes that catalyze the specific aminoacylation of tRNA by their cognate
amino acid in the initial step of ribosome-dependent protein biosynthesis.
FARSLA, also known as FRSA, CML33, FARSL or PheHA (phenylalanyl-tRNA
synthetase, alpha subunit), is a member of the class-II aminoacyl-tRNA
synthetase family and is highly expressed in proliferating cells of bone
marrow. FARSLA is a cytoplasmic phenylalanine-tRNA synthetase that functions
as a heterodimer consisting of a catalytic alpha-subunit and a regulatory
beta-subunit. The alpha-subunit is responsible for forming the amino acid
binding pocket, mediating the ATP/aminoacyl adenylate binding, and interacts
with the acceptor stem of the tRNA. FARSLA functions in a cell
cycle-dependent and differentiation-dependent manner. FARSLA (Phenylalanyl-tRNA synthetase alpha chain)
is an aminoacyl-tRNA synthetase. These are a class of enzymes that charge
tRNAs with their cognate amino acids. Cytoplasmic phenylalanine-tRNA
synthetase is a heterodimer consisting of a catalytic alpha subunit, FARSLA,
and a regulatory beta subunit, FARSLB. This protein has been shown to be
expressed in a tumor-selective and cell cycle stage- and
differentiation-dependent manner, the first member of the tRNA synthetase
family shown to exhibit this type of regulated expression. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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