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簡要描述：XRN1蛋白抗體免 疫 原；KLH conjugated synthetic peptide derived from human XRN1: 1501-1600/1706
產(chǎn)品型號(hào)：GOY-01K5031廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：173產(chǎn)品分類
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XRN1蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
XRN1蛋白抗體 | XRN1 | GOY-01K5031 |
商品屬性：
英文名稱: XRN1
中文名:XRN1蛋白抗體
別 名；XRN1_HUMAN; Dhm2;
mXRN1; SEP1; Strand-exchange protein 1 homolog; 5'-3' exoribonuclease 1.
研究領(lǐng)域；染色質(zhì)和核信號(hào) 表觀遺傳學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；193kDa
細(xì)胞定位；細(xì)胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human XRN1: 1501-1600/1706
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene encodes a member of the 5'-3'
exonuclease family. The encoded protein may be involved in
replication-dependent histone mRNA degradation, and interacts directly with
the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a
similar protein in yeast has been implicated in a variety of nuclear and
cytoplasmic functions, including homologous recombination, meiosis, telomere
maintenance, and microtubule assembly. Mutations in this gene are associated
with osteosarcoma, suggesting that the encoded protein may also play a role
in bone formation. Alternative splicing results in multiple transcript
variants. [provided by RefSeq, Sep 2013] Lamins are type V intermediate filament proteins
and are grouped into constitutively expressed B-type lamins and
developmentally regulated A-type lamins. Lamin-binding proteins in the
nuclear lamina and the nuclear interior include several protein families
and/or types of proteins in higher eukaryotes such as the inner nuclear
membrane proteins, lamin B receptor, emerin, MANI, three isoforms of
lamina-associated polypeptide 1 (LAP 1), and several isoforms of LAP 2. Up to
six LAP 2 isoforms derive from a single gene by alternative splicing in
mammals and various isoforms have been described in Xenopus. The best
characterized LAP2 isoforms are the inner nuclear membrane protein LAP 2 beta
and the nucleoplasmic protein LAP 2 alpha, which are identical in their
N-terminal 187-amino acid constant region but differ in their C termini. LAP
2 alpha specifically interacts with A-type lamins within the nuclear interior
as part of a detergent- and salt-resistant nucleoskeletal structure. Subunit: Interacts with LMNA, BANF1 and RB1 and with
chromosomes. Associates directly or indirectly with lamins at specific
cell-cycle stages. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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