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簡要描述：ZSWIM7蛋白抗體免 疫 原；KLH conjugated synthetic peptide derived from human ZSWIM7: 21-120/140
產(chǎn)品型號：GOY-01K5681廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：182產(chǎn)品分類
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ZSWIM7蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
ZSWIM7蛋白抗體 | ZSWIM7 | GOY-01K5681 |
商品屬性：
英文名稱: ZSWIM7
中文名:ZSWIM7蛋白抗體
別 名；SWIM
domain-containing and Srs2-interacting protein 1 homolog; SWIM
domain-containing Srs2-interacting protein 1; SWIM-type zinc finger
domain-containing protein 7; SWS1; Zinc finger SWIM domain-containing protein
7; Zinc finger, SWIM-type containing 7; zswim7; ZSWM7_HUMAN.
研究領(lǐng)域；細(xì)胞生物 鋅指蛋白 表觀遺傳學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；15kDa
細(xì)胞定位；細(xì)胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ZSWIM7: 21-120/140
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
ZSWIM7 is a 140 amino acid nuclear protein that
contains a SWIM-type zinc finger and belongs to the SWS1 family. ZSWIM7
interacts with Rad51D, and plays a role in the early stages of the homologous
recombination repair (HRR) pathway that occurs during double-stranded DNA
breaks. The gene encoding ZSWIM7 maps to human chromosome 17, which comprises
over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor
suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.
Malfunction or loss of p53 expression is associated with malignant cell
growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA
repair, though specifically it is recognized as a genetic determinant of
early onset breast cancer and predisposition to cancers of the ovary, colon,
prostate gland and fallopian tubes. Involved in early stages of the homologous
recombination repair (HRR) pathway of double-stranded DNA breaks arising
during DNA replication or induced by DNA-damaging agents. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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