簡要描述:磷酸化細(xì)胞外信號調(diào)節(jié)激酶5抗體免疫原 KLH conjugated synthesised phosphopeptide derived from human ERK5 around the phosphorylation site of Thr218 + Tyr220
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磷酸化細(xì)胞外信號調(diào)節(jié)激酶5抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
磷酸化細(xì)胞外信號調(diào)節(jié)激酶5抗體 | phospho-ERK5 (Thr218 + Tyr220) | GOY-01K2020 |
商品屬性:
英文名稱: phospho-ERK5 (Thr218 + Tyr220)
中文名:磷酸化細(xì)胞外信號調(diào)節(jié)激酶5抗體
英文別名 ERK5
(phospho T218 + Y220); ERK5 (phospho Thr218 + Tyr220); Big MAP kinase 1; BMK 1;
BMK 1 kinase; BMK-1; BMK1; BMK1 Kinase; EC 2.7.11.24; ERK 4; ERK 5; ERK4;
Extracellular Signal Regulated Kinase 5; Extracellular signal-regulated kinase
5; MAP kinase 7; MAPK 7; MAPK7; Mito Activated Protein Kinase 7; Mito-activated
protein kinase 7; MK07_HUMAN; OTTHUMP00000065906; OTTHUMP00000065907; PRKM 7;
PRKM7; PROTEIN KINASE, MITO-ACTIVATED, 7.
交叉反應(yīng):Human,
Mouse, Rat, Dog, Pig, Cow, Sheep, GuineaPig
標(biāo)記:Unconjugated
抗體來源: Rabbit
抗體類型:Polyclonal
免疫原 KLH
conjugated synthesised phosphopeptide derived from human ERK5 around the
phosphorylation site of Thr218 + Tyr220
蛋白細(xì)胞定位: 細(xì)胞核,細(xì)胞漿
純化方法: affinity
purified by Protein A
亞型 IgG
性狀: Liquid
濃度: 1mg/ml
儲存液: 0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件: Shipped
at 4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
研究領(lǐng)域: 腫瘤 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 激酶和磷酸酶
產(chǎn)品介紹:
The protein encoded by this e is a member of the
MAP kinase family. MAP kinases act as an integration point for multiple
biochemical signals, and are involved in a wide variety of cellular processes
such as proliferation, differentiation, transcription regulation and
development. This kinase is specifically activated by mito-activated protein
kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling
processes of various receptor molecules including receptor type kinases, and
G protein-coupled receptors. In response to extracelluar signals, this kinase
translocates to cell nucleus, where it regulates e expression by
phosphorylating, and activating different transcription factors. Four
alternatively spliced transcript variants of this e encoding two distinct
isoforms have been reported. [provided by RefSeq, Jul 2008] |
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重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺,能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
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