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簡要描述：5-氨基乙酰丙酸合酶1抗體免疫原：KLH conjugated synthetic peptide derived from human ALAS2/ALAS-E
產(chǎn)品型號：GOY-01K4173廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：211產(chǎn)品分類
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5-氨基乙酰丙酸合酶1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
5-氨基乙酰丙酸合酶1抗體 | ALAS-E | GOY-01K4173 |
商品屬性：
英文名稱: ALAS-E
中文名:5-氨基乙酰丙酸合酶1抗體
英文別名 ：5-aminolevulinate
synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase;
ALAS E; ALASE; ANH1; Delta aminolevulinate synthase; XLSA; 5 aminolevulinic
acid synthase 2; 5-aminolevulinate synthase 2; 5-aminolevulinate synthase;
5-aminolevulinate synthase 2; Alas 2; ALAS; ALAS E; ALAS, erythroid; ALASE;
Aminolevulinate, delta-, synthase 2; Aminolevulinic acid synthase 2, erythroid;
ANH1; ASB; Delta ALA synthase 2; Delta ALA synthetase; Delta aminolevulinate
synthase 2; Delta aminolevulinate synthase; Erythroid specific ALAS; FLJ93603;
XLDPP; XLSA.
交叉反應 ：Human,
Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
標記 ：Unconjugated
抗體來源：Rabbit
抗體類型：Polyclonal
免疫原：KLH
conjugated synthetic peptide derived from human ALAS2/ALAS-E
蛋白細胞定位：細胞漿
純化方法：affinity
purified by Protein A
亞型：IgG
性狀：Liquid
濃度：1mg/ml
儲存液：0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件：Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
背景資料5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS,
an enzyme catalyzing the first step of the heme biosynthetic pathway in
mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of
hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a
housekeeping protein which mediates synthesis of early heme in the mitochondria
of most cells. Succinyl CoA associates with ALAS-E in protein conformation
change and translocation of ALAS-E into the mitochondria and does not interact
with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear
activators such as GATA-1, NF-E2 and EKLF. Since the ALAS e maps to the X
chromosome, mutation of the e leads to the pyridoxine-refractory X-linked
sideroblastic anemia.
產(chǎn)品介紹:
5-aminolevulinate synthase 1 (ALAS-H) and 2
(ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the
heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme,
ALAS-E, regulates the first step of hematopoietic cell differentation and
iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates
synthesis of early heme in the mitochondria of most cells. Succinyl CoA
associates with ALAS-E in protein conformation change and translocation of
ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E
5'-flanking region contains binding sites for nuclear activators such as
GATA-1, NF-E2 and EKLF. Since the ALAS e maps to the X chromosome, mutation
of the e leads to the pyridoxine-refractory X-linked sideroblastic anemia. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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