簡(jiǎn)要描述:鈣激活鉀通道蛋白β1抗體免疫原 KLH conjugated synthetic peptide derived from human Maxi Potassium channel beta
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鈣激活鉀通道蛋白β1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
鈣激活鉀通道蛋白β1抗體 | Maxi Potassium channel beta | GOY-01K5725 |
商品屬性:
英文名稱: Maxi Potassium channel beta
中文名:鈣激活鉀通道蛋白β1抗體
英文別名英文別名 Human, Mouse, Rat, Dog, Pig, Cow, Horse,
Rabbit, Sheep
標(biāo)記 Unconjugated
抗體來(lái)源 Rabbit
抗體類型 Polyclonal
免疫原 KLH conjugated synthetic peptide derived from
human Maxi Potassium channel beta
蛋白細(xì)胞定位 細(xì)胞膜
純化方法 affinity purified by Protein A
亞型 IgG
性狀 Liquid
濃度 1mg/ml
儲(chǔ)存液 0.01M TBS(pH7.4) with 1% BSA, 0.03%
Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store
at -20 °C for one year. Avoid repeated freeze/thaw
cycles.
產(chǎn)品介紹:
Potassium channels are a group of ubiquitously
expressed proteins that serve numerous functions in excitable and
non-excitable cells. One class of integral membrane potassium channels is the
large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+
differs from most other potassium channels in that its activation is
controlled by both increases in intracellular calcium and by membrane
depolarization. Maxi K+ dual activation is possible because of its structure.
The core of the channel, which is similar to other potassium channels, is a
Maxi K+ alpha homotetramer that contains both a voltage sensor and an
intracellular calcium binding domain. In vascular smooth muscle, an auxiliary
beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its
effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the
concentration of calcium required to keep the pore open. Maxi K+ beta is the
target for possible therapeutics because of its role in blood flow and blood
pressure regulation. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過(guò)程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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