簡(jiǎn)要描述:腫瘤/睪丸抗原2.2/睪丸抗原2.3抗體免 疫 原;KLH conjugated synthetic peptide derived from human BAGE2 and BAGE2: 55-109/109
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腫瘤/睪丸抗原2.2/睪丸抗原2.3抗體
產(chǎn)品名稱(chēng) | 英文名稱(chēng) | 貨號(hào) |
腫瘤/睪丸抗原2.2/睪丸抗原2.3抗體 | BAGE2 + BAGE3 | GOY-01K4189 |
商品屬性:
英文名稱(chēng): BAGE2 + BAGE3
中文名:腫瘤/睪丸抗原2.2/睪丸抗原2.3抗體
別 名;B melanoma
antigen 2; B melanoma antigen family, member 2; Cancer/testis antigen 2.2;
CT2.2; BAGE2_HUMAN; B melanoma antigen family member 3; B melanoma antigen 3;
BAGE3; BAGE3_HUMAN; Cancer/testis antigen 2.3; Cancer/testis antigen family 2
member 3; CT2.3.
研究領(lǐng)域;腫瘤 細(xì)胞生物 免疫學(xué)
抗體來(lái)源;Rabbit
克隆類(lèi)型;Polyclonal
交叉反應(yīng);(predicted:
Human, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;10kDa
細(xì)胞定位;分泌型蛋白
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human BAGE2 and BAGE2: 55-109/109
亞 型;IgG
純化方法;affinity
purified by Protein A
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Members of the BAGE gene family encode antigens
that are recognized by cytotoxic T lymphocytes and are also known as CT
(cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3
gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or
juxtacentromeric movements.Generally, BAGE proteins are silent in all normal
tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2
and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3
(respectively), are 109 amino acid secreted proteins that are expressed in
22% of melanomas, lung and bladder carcinomas, and are also expressed in
normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are
most likely silenced by DNA methylation and/or chromatin compaction in normal
tissues other than testis. Function: Unknown. Candidate gene encoding tumor antigens. |
多克隆抗體制備:
我公司合成抗原,保證陽(yáng)性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測(cè)結(jié)果是陽(yáng)性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶(hù)節(jié)約成本。
鼠單克隆抗體制備:
客戶(hù)可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專(zhuān)業(yè)的建議。在制備過(guò)程中,與客戶(hù)互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽(yáng)性血清檢測(cè)達(dá)到合同要求的同時(shí),也能滿足客戶(hù)抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶(hù)節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無(wú)法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶(hù)提供各種類(lèi)型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶(hù)提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開(kāi)發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶(hù)量身定制的專(zhuān)業(yè)服務(wù),主要面向工業(yè)客戶(hù)。
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