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簡要描述：ATP6V1B2蛋白抗體免 疫 原；KLH conjugated synthetic peptide derived from human ATP6V1B2: 51-150/511
產(chǎn)品型號：GOY-01K4404廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：534產(chǎn)品分類
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ATP6V1B2蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
ATP6V1B2蛋白抗體 | ATP6V1B2 | GOY-01K4404 |
商品屬性：
英文名稱: ATP6V1B2
中文名:ATP6V1B2蛋白抗體
別 名；V-ATPase B2;
ATP6B1B2; ATP6B2; ATP6V1 B2; ATP6V1B 2; ATP6V1B2; ATPase H+ transporting
lysosomal 56/58kDa V1 subunit B isoform 2; ATPase H+ transporting lysosomal
56/58kDa V1 subunit B2; ATPase H+ transporting, lysosomal (vacuolar proton
pump) beta polypeptide 56/58kD isoform 2; ATPase, H+ transporting, lysosomal V1
subunit B2; brain isoform; Endomembrane proton pump 58 kDa subunit; H+
transporting two sector ATPase; HO 57; HO57; V ATPase B2 subunit; V ATPase
subunit B 2; V type proton ATPase subunit B, brain isoform; V-ATPase subunit B
2; V-type proton ATPase subunit B; Vacuolar ATP synthase subunit B brain
isoform; Vacuolar H+ ATPase 56,000 subunit; Vacuolar H+ ATPase 56000 subunit;
Vacuolar H+ATPase B2; Vacuolar proton pump subunit B 2; VAT B2; VATB 2; VATB;
VATB2; VATB2_HUMAN; Vma 2; Vma2; VPP 3; VPP3.
研究領(lǐng)域；腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 新陳代謝 表觀遺傳學(xué)
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；56kDa
細(xì)胞定位；細(xì)胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ATP6V1B2: 51-150/511
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Vacuolar-type H+-ATPase (V-ATPase) is a
multisubunit enzyme responsible for acidification of eukaryotic intracellular
organelles. V-ATPases pump protons against an electrochemical gradient, while
F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1
domain, which is responsible for ATP hydrolysis, and a integral V0 domain,
which is responsible for proton translocation, compose V-ATPase. Nine
subunits (A–H) make up the V1 domain and
five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase,
V-ATPase most likely operates through a rotary mechanism. The V-ATPase V1 B
subunit exists as two isoforms. In the inner ear, the V-ATPase B1 isoform
functions in proton secretion and is required to maintain proper endolymph pH
and normal auditory function. The gene encoding the human V-ATPase B1 isoform
maps to chromosome 2cen-q13. Mutations in this gene cause distal renal tubular
acidosis associated with sensorineural deafness. The V-ATPase B2 isoform is
expressed in kidney and is the only B isoform expressed in osteoclasts. The
gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21. Function: Non-catalytic subunit of the peripheral V1 complex
of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of
intracellular compartments in eukaryotic cells. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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