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簡要描述：凋亡相關蛋白TGFb信號抗體免 疫 原；KLH conjugated synthetic peptide derived from human ARTS: 91-150/478
產(chǎn)品型號：GOY-01K2155廠商性質：科研更新時間：2023-10-24 00:00:00訪 問 量：499產(chǎn)品分類
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凋亡相關蛋白TGFb信號抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
凋亡相關蛋白TGFb信號抗體 | ARTS/SEPT4 | GOY-01K2155 |
商品屬性：
英文名稱: ARTS/SEPT4
中文名:凋亡相關蛋白TGFb信號抗體
別 名；Apoptosis Related
Protein TGFb Signalling; Apoptosis-related protein in the TGF-beta signaling
pathway; ARTS; bradeion; Bradeion beta; Brain protein H5; CE5B3; CE5B3 beta;
cell division control-related protein 2; cerebral protein 7; H5 antibody
hCDCREL-2; hucep-7; peanut-like 2; Peanut-like protein 2; PNUTL2; SEPT4;
SEPT4_HUMAN; septin 4; Septin-4.
研究領域；細胞生物 細胞凋亡 細胞周期蛋白
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Rabbit, Sheep, )
產(chǎn)品應用；WB=1:500-2000
ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；55kDa
細胞定位；細胞核 細胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ARTS: 91-150/478
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
This gene is a member of the septin family of
nucleotidebinding proteins, originally described in yeast as cell divisioncycle
regulatory proteins. Septins are highly conserved in yeast,Drosophila, and
mouse, and appear to regulate cytoskeletalorganization. Disruption of septin
function disturbs cytokinesisand results in large multinucleate or polyploid
cells. This gene ishighly expressed in brain and heart. Alternatively
splicedtranscript variants encoding different isoforms have been describedfor
this gene. One of the isoforms (known as ARTS) is distinct; itis localized to
the mitochondria, and has a role in apoptosis andcancer. [provided by RefSeq,
Nov 2010]. Aminopeptidase that plays a central role in
peptide trimming, a step required for the generation of most HLA class
I-binding peptides. Peptide trimming is essential to customize longer
precursor peptides to fit them to the correct length required for
presentation on MHC class I molecules. Strongly prefers substrates 9-16
residues long. Rapidly degrades 13-mer to a 9-mer and then stops.
Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic
C-terminus, while it has weak activity toward peptides with charged
C-terminus. May play a role in the inactivation of peptide hormones. May be
involved in the regulation of blood pressure through the inactivation of
angiotensin II and/or the generation of bradykinin in the kidney. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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