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簡要描述：次要組織相容性抗原HA 1抗體免 疫 原；KLH conjugated synthetic peptide derived from human ARHGAP45: 5-100/1136
產(chǎn)品型號：GOY-01K5029廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：507產(chǎn)品分類
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次要組織相容性抗原HA 1抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
次要組織相容性抗原HA 1抗體 | ARHGAP45 | GOY-01K5029 |
商品屬性：
英文名稱: ARHGAP45
中文名:次要組織相容性抗原HA 1抗體
別 名；HLA HA1;
HMHA1_HUMAN; Rho GTPase-activating protein 45; HMHA1; KIAA0223; mHag HA-1;
Minor histocompatibility antigen HA 1; Minor histocompatibility protein HA 1.
研究領域；免疫學 轉(zhuǎn)運蛋白 淋巴細胞 t-淋巴細胞
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；(predicted:
Human, Mouse, Rat, Dog, Pig, Cow, Sheep, )
產(chǎn)品應用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；125kDa
細胞定位；細胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ARHGAP45: 5-100/1136
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Major histocompatibility complex (MHC) molecules,
which include human leukocyte antigens (HLAs), form an integral part of the
immune response system. They are cell-surface receptors that bind foreign
peptides and present them to cytotoxic T lymphocytes (CTLs). Minor
histocompatibility antigens can form an immune response upon recognition by
certain T-cells when complexed with MHC molecules. HA-1 (minor
histocompatibility protein HA-1), also known as HA-1, HLA-HA1 or HMHA1, is a
1,136 amino acid GTPase activator of Rho-type GTPases. Expressed in dendritic
cells, epidermal Langerhans cells, hematopoietic cells, peripheral blood
mononuclear cells and all leukemia and lymphoma cell lines, HA-1 is also
found in various solid tissues and tumors. Highly phosphorylated, HA-1
contains one Rho-GAP domain, a single phorbol-ester/DAG-type zinc finger and
is encoded by a gene located on human chromosome 19p13.3. The minor histocompatibility antigen (mHags), HA-1
is a immunogenic alloantigen shown to be responsible for graft-versus-host
disease (GVHD) in HLA-identical bone marrow transplantation. The antigen has
two known alleles resulting in a single amino acid polymorphism. The HA-1H
allele encodes histidine, whereas the HA-1R allele encodes arginine. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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