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簡要描述：轉錄激活蛋白2α/TFAP2α/AP-2α抗體免 疫 原；KLH conjugated synthetic peptide derived from human AP2 alpha
產(chǎn)品型號：GOY-01K0130廠商性質：科研更新時間：2023-10-24 00:00:00訪 問 量：569產(chǎn)品分類
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轉錄激活蛋白2α/TFAP2α/AP-2α抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
轉錄激活蛋白2α/TFAP2α/AP-2α抗體 | AP2 alpha | GOY-01K0130 |
商品屬性：
英文名稱: AP2 alpha
中文名:轉錄激活蛋白2α/TFAP2α/AP-2α抗體
別 名；Activating
enhancer binding protein 2 alpha; Activating enhancer-binding protein 2-alpha;
Activator protein 2; AP 2; AP 2 transcription factor; AP 2alpha; AP-2; AP-2
transcription factor; AP2; AP2 Transcription Factor; AP2-alpha; AP2A_HUMAN;
AP2TF; BOFS; Clathrin Adaptor Protein Complex; FLJ51761; TFAP 2; TFAP 2A;
TFAP2; TFAP2A; Transcription factor AP 2 alpha (activating enhancer binding
protein 2 alpha); Transcription factor AP 2 alpha; Transcription factor
AP-2-alpha; Transcription factor AP2 alpha.
研究領域；腫瘤 免疫學 信號轉導 細胞凋亡 轉錄調節(jié)因子
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；Mouse, (predicted: Human, Rat, Chicken,
Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用；WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；48kDa
細胞定位；細胞核
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human AP2 alpha
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The protein encoded by this gene is a transcription
factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein
functions as either a homodimer or as a heterodimer with similar family
members. This protein activates the transcription of some genes while
inhibiting the transcription of others. Defects in this gene are a cause of
branchiooculofacial syndrome (BOFS). Three transcript variants encoding
different isoforms have been found for this gene. Function: Sequence-specific DNA-binding protein that
interacts with inducible viral and cellular enhancer elements to regulate
transcription of selected genes. AP-2 factors bind to the consensus sequence
5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important
biological functions including proper eye, face, body wall, limb and neural
tube development. They also suppress a number of genes including MCAM/MUC18,
C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early
morphogenesis of the lens vesicle. Together with the CITED2 coactivator,
stimulates the PITX2 P1 promoter transcription activation. Associates with
chromatin to the PITX2 P1 promoter region. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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