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簡要描述：錨蛋白重復結構域蛋白17抗體免 疫 原；KLH conjugated synthetic peptide derived from human ANKRD17: 1501-1600/2603
產品型號：GOY-01K4216廠商性質：科研更新時間：2023-10-24 00:00:00訪 問 量：593產品分類
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錨蛋白重復結構域蛋白17抗體
產品名稱 | 英文名稱 | 貨號 |
錨蛋白重復結構域蛋白17抗體 | ANKRD17 | GOY-01K4216 |
商品屬性：
英文名稱: ANKRD17
中文名:錨蛋白重復結構域蛋白17抗體
別 名；ANKRD 17;
ANKRD-17; Ankyrin repeat domain protein 17; Ankyrin repeat domain-containing
protein 17; ANR17_HUMAN; FLJ22206; Gene trap ankyrin repeat; Gene trap ankyrin
repeat protein; GTAR; KIAA0697; NY BR 16; Serologically defined breast cancer
antigen NY-BR-16。
研究領域；細胞生物 細胞周期蛋白 細胞分化 表觀遺傳學
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應；(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用；ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復）
not yet tested in
other applications.
optimal dilutions/concentrations
should be determined by the end user.
理論分子量；274kDa
細胞定位；細胞核 細胞漿
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human ANKRD17: 1501-1600/2603
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M TBS(pH7.4)
with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產品介紹:
ANKRD17 is a 2,603 amino acid protein that
contains 25 ankyrin repeats and one KH domain. ANKRD17 is expressed in bone
marrow and is thought to be involved in liver development. ANKRD17 localizes
to the cytoplasm and the nucleus. ANKRD17 exists as five alternatively
spliced isoforms that are encoded by a gene which maps to human chromosome 4.
Representing approximately 6% of the human genome, chromosome 4 contains
nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an
expanded glutamine tract in cases of Huntington's disease, is on chromosome
4. FGFR-3 is also encoded on chromosome 4 and has been associated with
thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.
Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic
acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the
largest gene deserts (regions of the genome with no protein encoding genes)
and has one of the two lowest recombination frequencies of the human
chromosomes. Earliest specific in situ marker of hepatic
differentiation during embryogenesis, useful for characterization of
inductive events involved in hepatic specification (By similarity). Target of
enterovirus 71 which is the major etiological agent of HFMD (hand, foot and
mouth disease). |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結果是陽性。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應用驗證需求。技術服務實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務:
重組抗體技術使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務，包含鼠源單克隆抗體構建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務。
單項免疫學及檢測服務:
我公司也為客戶提供單項免疫學和檢測服務，如動物免疫、動物飼養(yǎng)、抗體修飾服務（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務。
抗體定制服務:
已注冊商標，主要用于抗體藥物發(fā)現和開發(fā)，是我公司針對有特定應用要求和各種模型測試的客戶量身定制的專業(yè)服務，主要面向工業(yè)客戶。
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