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簡(jiǎn)要描述：COPA蛋白抗體免 疫 原；KLH conjugated synthetic peptide derived from human COPA/alpha COP I: 451-550/1224
產(chǎn)品型號(hào)：GOY-01K1176廠商性質(zhì)：科研更新時(shí)間：2023-10-24 00:00:00訪 問 量：594產(chǎn)品分類
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COPA蛋白抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
COPA蛋白抗體 | alpha COP I | GOY-01K1176 |
商品屬性：
英文名稱: alpha COP I
中文名:COPA蛋白抗體
別 名；Alpha coat
protein; Alpha COP; Alpha COPI; AlphaCOP; Coatomer protein complex subunit
alpha; Coatomer subunit alpha; COP A; COP I alpha; COPA; COPI alpha; FLJ26320;
HEP COP; HEPCOP; Proxenin; Xenin; Xenopsin-related peptide; COPA_HUMAN.
研究領(lǐng)域；細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用；ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；138kDa
細(xì)胞定位；細(xì)胞漿 細(xì)胞膜 分泌型蛋白
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human COPA/alpha COP I: 451-550/1224
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
COPA (alpha-coat protein) is processed to produce
Xenin. Xenin stimulates exocrine pancreatic secretion to affect small and
large intestinal motility, and inhibits pentagastrin-stimulated secretion of
acid. In the gut, Xenin interacts with the neurotensin receptor. Membrane and
vesicular trafficking in the early secretory pathway are mediated by
non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles
mediate retrograde transport from the Golgi back to the ER and intra-Golgi
transport. The cytosolic precursor of the COPI coat, the heptameric coatomer
complex, is composed of two subcomplexes. The first consists of the COPB,
COPG, COPD and COPZ subunits (also known as b-, g-, d- and z-COP,
respectively), which are distantly homologous to AP Clathrin adaptor
subunits. The second consists of the COPA, b'-COP and COPE subunits (also
known as a-COP, COPP and e-COP, respectively). Function: The coatomer protein complex, alpha subunit (COPA)
is a cytosolic protein complex that binds to dilysine motifs and reversibly
associates with Golgi non-clathrin-coated vesicles. This interaction mediates
biosynthetic protein transport from the ER, via the Golgi up to the trans
Golgi network. The coatomer complex is required for budding from Golgi
membranes, and is essential for the retrograde Golgi-to-ER transport of
dilysine-tagged proteins. In mammals, the coatomer can only be recruited by
membranes associated to ADP-ribosylation factors, small GTP-binding proteins;
the complex also influences the Golgi structural integrity, as well as the
processing, activity, and endocytic recycling of LDL receptors. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價(jià)達(dá)到1：32000，由蛋白抗原制備的多抗，保證WB檢測(cè)結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行，我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中，與客戶互動(dòng)驗(yàn)證，確保最終制備的抗體ELISA陽性血清檢測(cè)達(dá)到合同要求的同時(shí)，也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià)，按節(jié)點(diǎn)收費(fèi)，為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測(cè)序、重組抗體表達(dá)等先進(jìn)平臺(tái)，能為客戶提供各種類型的重組抗體表達(dá)服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá)，抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測(cè)服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測(cè)服務(wù)，如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標(biāo)記）、以及ELISA，WB，IHC，DB等檢測(cè)服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo)，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對(duì)有特定應(yīng)用要求和各種模型測(cè)試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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