簡要描述:gp130結(jié)合蛋白GAM抗體免 疫 原;KLH conjugated synthetic peptide derived from human TLE5/Amino-terminal enhancer of split: 21-120/197
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gp130結(jié)合蛋白GAM抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
gp130結(jié)合蛋白GAM抗體 | AES | GOY-01K1158 |
商品屬性:
英文名稱: AES
中文名:gp130結(jié)合蛋白GAM抗體
別 名;Aes 1;
Amino-terminal enhancer of split; Aes 2; aes; AES_HUMAN; Aes1; Aes2; Amino
Enhancer of Split; Amino terminal enhancer of split; Amino-terminal enhancer of
split; Esp 1; Esp1; Gp130 associated protein GAM; Gp130-associated protein GAM;
GRG 5; GRG; GRG protein; GRG5; Protein ESP 1; Protein ESP1; Protein GRG; TLE 5;
TLE5.
研究領(lǐng)域;細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 干細(xì)胞 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Mouse, Rat, Chicken, Cow, Sheep, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;22kDa
細(xì)胞定位;細(xì)胞核
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human TLE5/Amino-terminal enhancer of
split: 21-120/197
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項;This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
TLE5 is a 197 amino acid nuclear protein that
belongs to the TLE family. Expressed predominately in fetal brain, liver,
lung, heart and kidney and in adult muscle, TLE5 functions as either a
homooligomer or a heterooligomer with other TLE family members and, through this
association, dominantly represses the expression of TLE genes. In addition,
TLE5 can repress NFkB-regulated gene expression and is thought to play an
important role in initiating and maintaining cell differentiation events. Two
isoforms of TLE5 exist due to alternative splicing events. Function: Acts as dominant repressor towards other family
members. Inhibits NF-kappa-B-regulated gene expression. May be required for
the initiation and maintenance of the differentiated state. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價,按節(jié)點收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進(jìn)行,我公司將為您的項目提供專業(yè)的建議。在制備過程中,與客戶互動驗證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時,也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價,按節(jié)點收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺,能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項免疫學(xué)和檢測服務(wù),如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
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