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簡要描述：5-羥色胺受體3D抗體免 疫 原；KLH conjugated synthetic peptide derived from human 5HT3D Receptor: 141-250/454
產(chǎn)品型號：GOY-01K0639廠商性質(zhì)：科研更新時間：2023-10-24 00:00:00訪 問 量：595產(chǎn)品分類
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5-羥色胺受體3D抗體
產(chǎn)品名稱 | 英文名稱 | 貨號 |
5-羥色胺受體3D抗體 | 5HT3D Receptor | GOY-01K0639 |
商品屬性：
英文名稱: 5HT3D Receptor
中文名:5-羥色胺受體3D抗體
別 名；5
hydroxytryptamine receptor 3D; 5-hydroxytryptamine receptor 3 subunit D; 5HT3D;
HTR3D; MGC119636; MGC119637; Serotonin 5-HT-3D receptor; Serotonin receptor 3D;
5HT3D_HUMAN.
研究領(lǐng)域；神經(jīng)生物學 細胞膜受體 G蛋白偶聯(lián)受體 新陳代謝 G蛋白信號
抗體來源；Rabbit
克隆類型；Polyclonal
交叉反應(yīng)；(predicted:
Human, )
產(chǎn)品應(yīng)用；WB=1:500-2000
ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量；48kDa
細胞定位；細胞膜
性 狀；Liquid
濃 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human 5HT3D Receptor: 141-250/454
<Extracellular>
亞 型；IgG
純化方法；affinity
purified by Protein A
緩 沖 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件；Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
Serotonin is a monoamine neurotransmitter that is
made in serotonergic neurons in the CNS (central nervous system) and is
important in the regulation of mood, sleep, vomiting, sexuality and appetite.
5-HT3 (5-hydroxytryptamine-3) receptor is the only ligand-gated ion channel
within the family of serotonin receptors. It is composed of five subunits consisting
of SR-3A, SR-3B, HTR3C, HTR3D and HTR3E. HTR3D (5-hydroxytryptamine receptor
3D), also known as Serotonin receptor 3D, is a 454 amino acid multi-pass
membrane protein that is one components of the pentaheteromeric complex that
forms the 5-HT3 receptor. HTR3D must be co-expressed with SR-3A to form a
functional 5-HT3 receptor complex on the plasma membrane. Until it is
complexed with SR-3A, HTR3D is localized within the endoplasmic reticulum.
Expression of HTR3D is restricted to kidney, colon and liver. There are three
different isoforms of HTR3D that are expressed as a result of alternative
splicing events. Function: This is one of the several different receptors for
5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a
neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated
ion channel, which when activated causes fast, depolarizing responses. It is
a cation-specific, but otherwise relatively nonselective, ion channel. |
多克隆抗體制備：
我公司合成抗原，保證陽性血清和抗體ELISA效價達到1：32000，由蛋白抗原制備的多抗，保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項目實際需求情況靈活選擇進行，我公司將為您的項目提供專業(yè)的建議。在制備過程中，與客戶互動驗證，確保最終制備的抗體ELISA陽性血清檢測達到合同要求的同時，也能滿足客戶抗體最終應(yīng)用驗證需求。技術(shù)服務(wù)實行分步報價，按節(jié)點收費，為客戶節(jié)約成本。
重組抗體表達服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能，而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達等先進平臺，能為客戶提供各種類型的重組抗體表達服務(wù)，包含鼠源單克隆抗體構(gòu)建及表達、更換恒定區(qū)亞型的嵌合抗體表達，抗體人源化改造及表達等服務(wù)。
單項免疫學及檢測服務(wù):
我公司也為客戶提供單項免疫學和檢測服務(wù)，如動物免疫、動物飼養(yǎng)、抗體修飾服務(wù)（如FITC，HRP等的標記）、以及ELISA，WB，IHC，DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊商標，主要用于抗體藥物發(fā)現(xiàn)和開發(fā)，是我公司針對有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù)，主要面向工業(yè)客戶。
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