">
簡要描述:5-羥色胺受體1E抗體免 疫 原;KLH conjugated synthetic peptide derived from human 5HT1E Receptor/SR-1E: 1-120/365
產(chǎn)品分類
Product Category相關(guān)文章
Related Articles詳細(xì)介紹
5-羥色胺受體1E抗體
產(chǎn)品名稱 | 英文名稱 | 貨號(hào) |
5-羥色胺受體1E抗體 | 5HT1E Receptor | GOY-01K2319 |
商品屬性:
英文名稱: 5HT1E Receptor
中文名:5-羥色胺受體1E抗體
別 名;SR-1E; 5
hydroxytryptamine (serotonin) receptor 1E; 5 hydroxytryptamine (serotonin)
receptor 1E G protein coupled; 5 hydroxytryptamine 1E receptor; 5-HT-1E;
5-hydroxytryptamine receptor 1E; HTR1E; S31; Serotonin receptor 1E;
5HT1E_HUMAN.
研究領(lǐng)域;神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) G蛋白偶聯(lián)受體 新陳代謝 G蛋白信號(hào)
抗體來源;Rabbit
克隆類型;Polyclonal
交叉反應(yīng);(predicted:
Human, Pig, Cow, Guinea Pig, )
產(chǎn)品應(yīng)用;ELISA=1:5000-10000
IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理論分子量;42kDa
細(xì)胞定位;細(xì)胞膜
性 狀;Liquid
濃 度;1mg/ml
免 疫 原;KLH
conjugated synthetic peptide derived from human 5HT1E Receptor/SR-1E: 1-120/365
<Extracellular>
亞 型;IgG
純化方法;affinity
purified by Protein A
緩 沖 液;0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件;Shipped at
4℃. Store at -20 °C for one
year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng);This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
產(chǎn)品介紹:
The members of the G-protein-coupled receptor
family are distinguished by their slow transmitting response to ligand
binding. These seven transmembrane proteins include the adrenergic, serotonin
and dopamine receptors. The effect of the signaling molecule can be
excitatory or inhibitory depending on the type of receptor to which it binds.
b-adrenergic bound to adrenaline activates adenylyl cyclase, while
a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like
the a2-adrenergic receptor, serotonin receptor functions are also mediated by
G proteins that inhibit the activity of adenylyl cyclase. The serotonin
receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within
the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Function: This is one of the several different receptors for
5-HT, a biogenic hormone that functions as a neurotransmitter, a hormone, and
a mitogen. The activity of this receptor is mediated by G proteins that
inhibit adenylate cyclase activity. The 5-HT1E receptor is expressed in human
cortex, caudate, putamen, and amygdala, as well as in dorsal root ganglia and
in coronary artery. ESTs have been isolated from human brain cancer
libraries. |
多克隆抗體制備:
我公司合成抗原,保證陽性血清和抗體ELISA效價(jià)達(dá)到1:32000,由蛋白抗原制備的多抗,保證WB檢測結(jié)果是陽性。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
鼠單克隆抗體制備:
客戶可根據(jù)項(xiàng)目實(shí)際需求情況靈活選擇進(jìn)行,我公司將為您的項(xiàng)目提供專業(yè)的建議。在制備過程中,與客戶互動(dòng)驗(yàn)證,確保最終制備的抗體ELISA陽性血清檢測達(dá)到合同要求的同時(shí),也能滿足客戶抗體最終應(yīng)用驗(yàn)證需求。技術(shù)服務(wù)實(shí)行分步報(bào)價(jià),按節(jié)點(diǎn)收費(fèi),為客戶節(jié)約成本。
重組抗體表達(dá)服務(wù):
重組抗體技術(shù)使制備人源化抗體和人源抗體成為可能,而這是其他常規(guī)的多克隆或單克隆抗體制備方法無法做到的。我公司已搭建好的抗體測序、重組抗體表達(dá)等先進(jìn)平臺(tái),能為客戶提供各種類型的重組抗體表達(dá)服務(wù),包含鼠源單克隆抗體構(gòu)建及表達(dá)、更換恒定區(qū)亞型的嵌合抗體表達(dá),抗體人源化改造及表達(dá)等服務(wù)。
單項(xiàng)免疫學(xué)及檢測服務(wù):
我公司也為客戶提供單項(xiàng)免疫學(xué)和檢測服務(wù),如動(dòng)物免疫、動(dòng)物飼養(yǎng)、抗體修飾服務(wù)(如FITC,HRP等的標(biāo)記)、以及ELISA,WB,IHC,DB等檢測服務(wù)。
抗體定制服務(wù):
已注冊(cè)商標(biāo),主要用于抗體藥物發(fā)現(xiàn)和開發(fā),是我公司針對(duì)有特定應(yīng)用要求和各種模型測試的客戶量身定制的專業(yè)服務(wù),主要面向工業(yè)客戶。
產(chǎn)品咨詢
歡迎您關(guān)注我們的微信了解更多信息
電話
微信掃一掃